Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...

The paper S.C. Kim et al., “Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA,” PNAS, 115:13318–23, 2018. Proponents of the RNA world theory argue that ...

Scientists have made a major discovery about ADAR1—a protein that controls RNA-induced immune responses—paving ...

Eric Siegel, a Ph.D. student in microbiologist Stephen Rich’s Laboratory of Medical Zoology and at the UMass Amherst-based New England Center of Excellence in Vector-borne Diseases (NEWVEC), has been ...

Researchers uncover new insights into the molecular mechanisms of ADAR1, a protein that regulates RNA-induced immune responses. Their findings could open new pathways for treating autoimmune diseases ...