The four main classes, which most people are treated with, target one of three viral proteins which control HIV’s lifecycle: reverse transcriptase, integrase and protease. Historically, most people ...

Dolutegravir is an HIV integrase strand transfer inhibitor (INSTI ... enzymes and therefore is associated with few drug interactions other than metformin and dofetilide. Dolutegravir should ...

The HIV treatment landscape has further evolved with the introduction of LAI therapies, offering alternatives to daily oral ...

The drugs are organized into six different classes ... Without the means to enter a cell, HIV cannot replicate. Integrase ...