Biologics targeting interleukin-12, -23, and -17 were associated with a lower rate of serious infections among older adults ...

Microglia, the brain's immune cells, usually serve as diligent guardians. They eliminate intruders such as microbes and clear ...

Getting seven experiments on the International Space Station requires a really good idea. Like a brand new way to attack ...

When interleukin-12 is added to the cell culture, it leads to a significant reduction in nerve fibers (pink) and oligodendrocytes, and thus to a decline in myelin (white).

IL-23, or IL-17 reduced serious infections, while tofacitinib increased infection risk, according to one study.

Ustekinumab is a human interleukin-12 and -23 antagonist indicated for multiple chronic inflammatory diseases. A biosimilar is a biological product that is approved based on data demonstrating ...

A new study reveals that IL-12, an inflammatory molecule, accelerates Alzheimer’s disease by damaging brain cells and preventing plaque clearance. Blocking IL-12 in mice halted disease-related changes ...