Biologics targeting interleukin-12, -23, and -17 were associated with a lower rate of serious infections among older adults ...

During this mission, the team will grow Janus base nanotubes that carry interleukin-12. Interleukin-12 is a protein already produced naturally by the human body, but only in small quantities. It ...

share their discovery that a cytokine called interleukin-12 (IL-12) acts like a switch to direct which antibody response B cells will generate. Both B-cell responses are biologically important ...

Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory ...

When interleukin-12 is added to the cell culture, it leads to a significant reduction in nerve fibers (pink) and oligodendrocytes, and thus to a decline in myelin (white).

IL-23, or IL-17 reduced serious infections, while tofacitinib increased infection risk, according to one study.

Ustekinumab is a human interleukin-12 and -23 antagonist indicated for multiple chronic inflammatory diseases. A biosimilar is a biological product that is approved based on data demonstrating ...

A new study reveals that IL-12, an inflammatory molecule, accelerates Alzheimer’s disease by damaging brain cells and preventing plaque clearance. Blocking IL-12 in mice halted disease-related changes ...