衣康酸是一种天然存在的物质,通过与免疫系统相互作用而具有抗炎作用。然而,衣康酸的弱点是它不容易穿透细胞。Majer团队花了几年时间开发一种治疗秃头的药物,通过开发基于衣康酸衍生物的前体药物克服了这一障碍,其中前体药物是一种仅在体内转化为活性药物的化合物。
Researchers have developed a compound that could potentially treat the autoimmune disorder alopecia areata, which causes hair loss leading to the formation of bald patches. The results confirm the ...
THE observation reported in the present note relates to an Aspergillus with yellow- to ochraceous-eoloured conidia. The mould does not appear to correspond entirely with any published description.
A research group, led by Dr. Pavel Majer from IOCB Prague, in collaboration with the laboratories of Barbara Slusher and Louis Garza at Johns Hopkins University, has developed a compound that could ...
The results of their study, recently published in the Journal of Medicinal Chemistry, confirm the efficacy of a series of prodrugs based on derivatives of itaconic acid, simply referred to as ...
The results of their study, recently published in the Journal of Medicinal Chemistry, confirm the efficacy of a series of prodrugs based on derivatives of itaconic acid, simply referred to as ...