生物通21 天
KAT6B 高表达可 “拯救” KAT6A 缺陷：解锁染色质调控新奥秘
为探究 KAT6A 和 KAT6B 功能关系，WEHI 的研究人员开展相关研究，发现过表达 Kat6b 可拯救 Kat6a 突变小鼠缺陷，为相关疾病治疗提供新思路。 在生命的微观世界里，基因的调控就像一场精密的交响乐演奏，每个音符（基因）都在特定的时间和空间奏响，共同谱写着 ...
BioWorld7 天
Shanghai Henlius Biologics divulges new KAT6A and KAT6B inhibitors
Shanghai Henlius Biologics Co. Ltd. has synthesized histone acetyltransferase KAT6A (monocytic leukemia zinc finger protein; MOZ; MYST-3) and/or histone acetyltransferase KAT6B (MOZ2; MYST-4) ...
BioWorld1 个月
KAT6A inhibition as new therapeutic strategy for IgE-mediated allergic diseases
Researchers from Shenzhen University have evaluated the potential antiallergic effects of the histone acetyltransferase KAT6A inhibitor WM-1119 on IgE-mediated mast cell activation and allergic ...
SBS3 年
"He was the second case in Sydney", Japanese mum tries to raise awareness of a rare genetic ...
Sydney-based Japanese mum Ryoko Tacadena has a 3-year-old son, Shinji, who has a rare genetic disorder called KAT6A Syndrome. Sydney-based Japanese mum Ryoko Tacadena has a 3-year-old son ...