本研究针对KRAS突变型非小细胞肺癌(NSCLC)中STK11/LKB1缺失导致的治疗抵抗问题，通过多组学分析揭示了LKB1-NUAK1-PP1B信号轴调控JNK ...

正常情况下，卵巢的发育和功能依赖于精细的调控机制，其中自噬（Autophagy）起着至关重要的作用 ... SCPN 改善 PCOS 大鼠卵巢自噬相关成分 SIRT1/AMPK α1,2 /LKB1 水平 研究检测了卵巢中 SIRT1、p - Thr 172 AMPK α1,2 和 p - Ser 428 LKB1 的水平，发现 PCOS 大鼠这些成分水平显著 ...

In 2000, it was suggested to me that “Autophagy will be the wave of the future; it will become the new apoptosis.” Few people would have agreed at the time, but this statement turned out to be ...