AbbVie has claimed FDA approval for Emblaveo, a new antibiotic product to treat complicated intra-abdominal infections (cIAI) ...

AbbVie receives US FDA approval for Emblaveo to treat adults with complicated intra-abdominal infections with limited or no treatment options: North Chicago, Illinois Monday, Febr ...

They introduced random peptide libraries into three loops close to the active site of β-lactamase and selected ... In a competitive assay, the altered enzyme was capable of detecting PSA at ...

The researchers used CARBonAra to design new variants of the TEM-1 β-lactamase enzyme, which is involved in the development of antimicrobial resistance. Some of the predicted sequences ...

Addresses the significant threat of antimicrobial resistance.

Plasmid borne genes encoding modifying enzymes such as beta-lactamases, that confer resistance to penicillins and related antibiotics, or, more recently, phosphoethanolamine transferases, that confer ...

AbbVie has announced that the U.S. Food and Drug Administration (FDA) has approved EMBLAVEO (aztreonam and avibactam), as a ...

Australian synthetic biologists have developed a prototype for an innovative biosensor that can detect rare earth elements ...

The inhibitor prevents bacterial enzymes such as metallo-β-lactamases (MBLs) and serine-β-lactamases (SBLs) from breaking down the antibiotic before it has its desired effect to treat the infection.

Clavulanic acid is a beta-lactam, structurally related to penicillin, that may inactivate certain beta-lactamase enzymes. Take with meals. Base dose on amoxicillin component. Due to clavulanic ...