Increasing lactate concentrations in the colon are also associated with disease severity in people suffering from inflammatory bowel diseases. Lactate-induced killing of protective gut microbiome ...

Purpose: Increased blood lactate concentration has been suggested as a primary stimulus for the exercise-induced growth hormone response (EIGR). Patients with McArdle disease are unable to produce ...

Researchers have discovered that an enzyme can serve as an ideal target for developing new therapeutics against Lyme disease, and most likely other tick-borne diseases as well.

Researchers at Virginia Commonwealth University discovered an enzyme, lactate dehydrogenase , as a potential therapeutic target for Lyme disease.This enzyme plays a pivotal role in enabling the ...

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Lyme disease is the most commonly reported tick ... burgdorferi does not use thiamin as a cofactor and instead relies on lactate dehydrogenase (BbLDH) to convert pyruvate to lactate to balance ...

Researchers have identified BbLDH as a critical component for the survival and infectivity of Borrelia burgdorferi, the bacteria responsible for Lyme disease. The fundamental nature of BbLDH lies in ...

Researchers have discovered that an enzyme can serve as an ideal target for developing new therapeutics against Lyme disease, and ...

Lyme disease is the most commonly reported tick ... burgdorferi does not use thiamin as a cofactor and instead relies on lactate dehydrogenase (BbLDH) to convert pyruvate to lactate to balance ...