During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a ...

The single-stranded DNA binding (SSB ... present resulted from the processing of a DNA break or from normal lagging strand DNA synthesis? The answer to this question may simply be a matter ...

and another clamp loader called RFC in both human and yeast to thread the clamp onto the lagging strand. The clamp then closes and signals to the polymerases that they can begin replicating DNA.

In DNA replication, the "leading" strand forges ahead, adding letters as it goes, while the "lagging" strand follows behind, connecting the double helix in fits and starts. Biologists widely ...