The fragments of newly synthesized DNA along the lagging strand are called Okazaki fragments, named in honor of their discoverer, Japanese molecular biologist Reiji Okazaki. Okazaki and his ...

and another clamp loader called RFC in both human and yeast to thread the clamp onto the lagging strand. The clamp then closes and signals to the polymerases that they can begin replicating DNA.

DNA replication is one of the most basic processes ... whereas the other is called the lagging strand. The leading strand is synthesized continuously, as shown in Figure 5. In contrast, the ...

The helicase was observed to bind the DNA in a cyclic motion, pulling the tracking or leading strand through binding loops while directing the non-tracking or lagging strand out of the complex.

In DNA replication, the "leading" strand forges ahead, adding letters as it goes, while the "lagging" strand follows behind, connecting the double helix in fits and starts. Biologists widely ...