The difference between big holes and small holes is that a large patched area is more likely to concave or convex; worst case, someone could lean against it and push the patch right into the hole.

For a few months this summer, a large strip of Atlantic Ocean along the equator cooled at record speed. Though the cold patch ...

We present data on a large number of patients patch-tested with a large and evolving series of metals. Little has been published regarding many of the metals used in this patch test series.

Background: The standard allergen series used in patch testing contains metals that most commonly cause allergic contact dermatitis, but testing with additional metal allergens is warranted for ...