All lentivirus vectors produced in the VDL are produced in compliance with GLP standards. The production of a lentivirus begins with cloning the gene of interest (goi) into an entry plasmid of the ...

Viral gene delivery is a ubiquitous laboratory technique with a myraid of uses. Understanding the basics of gene delivery workflows, from vector selection and cloning to transduction, is a fundamental ...

Among these, lentivirus-based vectors, derived from the HIV-1 retrovirus, are of growing interest in gene and cell therapy, particularly in immuno-oncology, due to their ability to infect dividing ...

single-cell cloning, illustrating how the platform can accelerate the development of high-producing lentivirus packaging cell lines. You’ll also hear how this system ensures monoclonality within the ...

Figure 1: β-galactosidase expression in mouse liver following lentiviral transduction. We analysed liver toxicity in rodents by measuring the serum alanine aminotransferase (ALT) concentration ...

GBU is home to genome-wide libraries of open reading frames (ORFs), as well as shRNAs and gRNAs in lentiviral backbones, available for researchers in the Biocenter Finland network. We also provide ...