The lightsheet system is perfect for capturing 3D fluorescent images of organisms, tissue explants, and cell cultures over long periods. Basically, it shines a thin sheet of laser light on a slice of ...

LightSheet microscopy is a fluorescence technique that projects a thin ‘sheet’ of excitation light perpendicular to the direction of observation. This type of a system uses cylindrical optics to focus ...

Light-sheet fluorescence microscopy has become the leading method for imaging large, tissue-cleared samples in 3D, owing to its optical sectioning, reduced photodamage, and rapid acquisition.