In human cells, lipid droplets (LDs) predominantly contain either cholesteryl esters or triacylglycerols. This article ...

Scientists have discovered a new protein pathway involved in neurodegeneration by studying “mini-brain” organoids made from ...

Lipid bilayers in mammalian membranes can have a more asymmetric composition than previously thought, new research shows.

Lipid accumulation in tumor cells and nearby immune cells promotes immune suppression and therapy resistance in ...

However, some initially responsive tumors still develop recurrences. Researchers studied mouse models and found that TNBC ...

An Osaka Metropolitan University-led study demonstrated that Cdc42 (cell division cycle 42) plays a crucial role in the formation and maintenance of the morphological characteristics of quiescent ...

Are there key genes involved in TKI resistance in ccRCC? What mechanisms are associated with this development? A research team, led by Professor Ben Liu from the Department of Urology at the First ...

Once thought to be little more than blobs of fat inside eukaryotic cells, lipid droplets may in fact provide a first line of defence against invading pathogens, according to evidence published today ...

“Hepatic fat is a relatively simple process: Lipid droplets accumulate in the hepatocytes; but, in the pancreas, there are several ways by which fat may accumulate,” he said. One relates to ...

Results showed trehalose suppressed the hypertrophy of fat cells in both types of mice and increased lipid droplets in the intestinal epithelium: these were excreted in the mice’s faeces.

Researchers say they are exploring therapeutic options to block fatty acid accumulation and immunosuppressive signals between cancer cells and neutrophils.