Lissencephaly is a devastating genetic disease of children that affects the embryonic development of the brain. It is caused by haploinsufficiency of the Lis1 gene product, which seems to be ...

Lissencephaly (agyria) refers to a type of rare genetic condition that leads to brain changes during fetal development. An infant's brain lacks folds and is smoother than typical, and the head is ...

Lissencephaly is a spectrum of rare, genetic disorders in which the brain fails to develop its hallmark folds. The disorders are often associated with seizures and intellectual disability and ...