David Savitsky and colleagues in Japan have now shown that IRF5 contributes to murine lupus via its influence on B lymphocytes. B lymphocytes have been linked to the development of lupus ...

such as lymphoma, lupus, or leukemia. Lymphocytes are a type of leukocyte (white blood cells) produced in the bone marrow that make up anywhere from 18% to 42% of circulating white blood cells.