Acetylation of proteins, generally on lysine residues, via an acetyl-coenzyme A donor, can have functional consequences, as in proteins contained within chromatin and metabolic enzymes.

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

PDHX acetylation promotes tumor progression by disrupting PDC assembly and activating lactylation-mediated gene expression.

The histone tag, characterized by lysine 8 acetylation on histone H4, identifies a significant departure from the histone ...