A few examples of such loops have been described and are discussed below. Figure 4: Propagation of histone 3 lysine 27 trimethylation by polycomb repressive complex 2. Nuclear architecture and ...

Researchers have previously found that the methylation of one particular location, lysine-4, on histone H3, is closely correlated with turning genes "on." Knowing that this relationship exists ...

In a groundbreaking study led by Dr. Ying Chen and her team from Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, researchers have uncovered a novel mechanism behind endothelial ...

Histone post-translational modifications (PTMs) mediate the interplay between metabolism and epigenetics, influencing health and disease. Beyond acetylation, short-chain lysine acylations like ...

Setd2 is instrumental in the trimethylation of histone H3 lysine 36 (H3K36me3), a modification that influences gene expression and has been implicated in various cancers and developmental disorders.