Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged ...

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in Nature Communications on how the targeted suppression of lysosome function may lead to brain cancer therapy.

The discovery of lysosomes led to many new questions. The most critical question was: what was the physiological function of this "bag" of enzymes? The Function of Lysosomes One of the definitive ...

Kanazawa University, report in Nature Communications how the targeted suppression of lysosome function may lead to brain cancer therapy.

The Golgi apparatus functions as a molecular assembly line ... they are directed to their appropriate destinations — either lysosomes, storage vesicles, or the plasma membrane (Figure 2).

Because lysosome dysfunction is also a prominent ... STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation in lysosomal storage disorders ...

A new set of genes that contribute to Parkinson’s disease risk has been identified.

A new study shows that dysfunction of lysosomes can cause leakage of toxic substances within brain cells, contributing to ...

Evidence suggests that in Parkinson’s disease, a breakdown in lysosomal function allows lipids to build up within cells. Variants of the GBA1 gene, the strongest genetic risk factor for sporadic PD, ...

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in Nature Communications on how the targeted suppression of lysosome function may lead to brain cancer therapy.