Hosted on MSN1mon
Inability of cells to recycle fats can spell disease: Study reveals how a protein helps transport fats out of lysosomes
This bubble then merges with the lysosome, where the contents are broken ... leading to the buildup of waste inside cells and human diseases. "We're excited about the potential of this research ...
Nature2mon
Autophagy: from phenomenology to molecular understanding in less than a decade
Similarly, our knowledge regarding the connections between autophagy and human physiology has continued ... that helped lead to the discovery of the lysosome as a distinct entity in 1955 (see ...
Hosted on MSN2mon
Microglia digest large Alzheimer's plaques by spitting enzymes at them, preclinical study finds
"The microglial lysosomes secreted their contents ... they will assess whether human cells also use this process. Human induced pluripotent stem cells can mature into many types of cells ...
The Scientist2mon
A STING Operation in Safeguarding Cells from Stress
On screening human cells to identify proteins that shuttled from the ... because their activation coincided with genes that increased lysosome production. TFEB is also an ancient regulator of ...