Lysosome-related organelles (LROs) or granules are the main protease storage and processing organelles of the endolysosomal system. The range of proteases present in LROs is cell-type specific.

Similarly, our knowledge regarding the connections between autophagy and human physiology has continued ... that helped lead to the discovery of the lysosome as a distinct entity in 1955 (see ...

Feng Wei at the Institute of Biophysics, Chinese Academy of Sciences, has made significant strides in understanding the BORC complex, a key player in lysosome transport and localization.

This bubble then merges with the lysosome, where the contents are broken ... leading to the buildup of waste inside cells and human diseases. "We're excited about the potential of this research ...