De Duve named these new organelles "lysosomes" to reflect their lytic nature. That same year, Alex Novikoff from the University of Vermont visited de Duve´s laboratory. An experienced ...

Lysosomes, often reductively referred to as the "garbage disposals" of cells, play a pivotal role in our cells' digestive ...

The ER, Golgi apparatus, and lysosomes are all members of a network of membranes, but they are not continuous with one another. Therefore, the membrane lipids and proteins that are synthesized in ...

Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say. Holly Barker is a freelance journalist ...

A study reveals how glutamate drives tau accumulation in Alzheimer’s and related disorders. Researchers found that blocking the gene KCTD20 activates lysosomes, helping clear toxic tau proteins in lab ...