One of the factors that determine the success of the tetramer production is the binding affinity of the peptide for the MHC class I molecule. Unfortunately, we cannot accurately predict the binding ...

All expression plasmids containing MHC alleles will be retained at our facility and will be used for future production and distribution of tetramer reagents. Requestors incur the cost of peptide that ...

The yield from a tetramer preparation is variable, but typically the product is sufficient for hundreds of stainings, often thousands of stainings. The stability of MHC class I tetramers is variable ...

Recently developed major histocompatibility complex (MHC) multimer technologies allow visualization and isolation of antigen-specific T cells. However, functional analysis and in vivo transfer of ...