The team from Israel, the US, and China has developed a genetic method to reprogramme a type of immune cell, turning them ...

A new study reveals a surprising mechanism by which itaconate inhibits the active site of a peroxiredoxin enzyme to amplify redox signalling and the type I interferon response in macrophages.

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components ...

Currently there are no cures for rheumatoid arthritis (RA) which affects 40,000 people in Ireland. The disease costs an estimated €20,000 per patient, per year with an overall cost to the health ...

Through CRISPR-Cas9 gene editing and single-cell analysis, they zeroed in on a gene named Zeb2.

An international team of researchers from Israel, the United States, and China has developed a genetic method to ...