For example, we now routinely work with THP-1 macrophage cells after investing significant time optimising the conditions to work with this notoriously difficult cell line. Are all of the edited ...

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components ...

Macrophages, a type of white blood cell, adjust their molecular signaling ... The human immune system has two lines of defense. The innate immune system acts quickly and non-specifically to ...

This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.