While innate immunity is clearly understood to play a role in fighting infection, its significance in tissue homeostasis is more recently revealed. This can involve, for example, macrophages and ...

Pullulan nanogel, United Immunity’s nanoparticulate immuno-delivery system technology targets macrophages—a key component of innate immunity that have emerged as a novel drug target in immuno ...

Deciphering the gut biome's, including helminths', influence on human trained immunity will unlock novel immunotherapies harnessing the immune reprogramming potential of their secreted factors and ...

the innate immune system, consists of a variety of cell types, including natural killer (NK) cells, macrophages and dendritic cells, that serve as an initial line of defense against threats.

Macrophages are classical cells of the innate immune system that are crucial for the rapid detection and digestion of pathogens. They found that mRNA-based COVID-19-vaccinations cause a ...

Macrophages serve as the Swiss army knives of the innate immune system, switching between phenotypes to perform different functions in response to the surrounding environment. One of their key ...

Pheast Therapeutics has treated the first subject in a multi-centre Phase I trial for PHST001, aimed at treating advanced ...

and that this memory response was coming from an unexpected corner of the immune system. It turned out that epigenetic changes in macrophages-;innate immune cells that are among the first ...

When your body senses something is wrong—whether it's a damaged cell or a growing tumor—it can react in many ways. One of the most powerful is cellular senescence. This process stops a cell from ...

Pheast Therapeutics has treated the first patient in a phase 1 trial of PHST001, a novel macrophage checkpoint inhibitor for advanced solid tumors.

It's a meaningful step toward harnessing the full potential of the innate immune system in cancer." CD24 is a cell surface protein that plays a key role in tumor immune evasion by engaging Siglec-10, ...