“The platform has enabled us to develop a pipeline of novel therapeutic programs, targeting tumor-associated macrophages, based on either first-in-class targets or first-in-mechanism ...

Macrophages interact with T cells in order to bring about T cell activation in target organs, and are themselves activated by inflammatory messenger molecules (cytokines) produced by the T cells.

Our livers contain many different types of immune cells. New research by the team of Prof. Charlotte Scott (VIB-UGent Center for Inflammation Research) and colleagues now reveals that a specific ...

Scientists in the laboratory of Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of ...

The $4.9 billion acquisition of Forty Seven by Gilead is an example of the explosive excitement and investment into macrophage-directed therapies, utilizing CD47 checkpoint blockades ...

Our findings suggest that blocking the sodium channel or the MCP-1 receptor in macrophages could reduce the inflammation and tissue damage in LSDs. There are already drugs that target these ...

Research from VIB-UGent identifies lipid-associated macrophages and LAM-like Kupffer cells as critical for liver repair. The ...

This study unveiled the role of Lrrk2 gene in regulating macrophage polarization and immune response. This finding provides ...