Of 68 consecutive patients treated in the French M7 protocol for medulloblastoma, 23 presented with metastatic disease. They were uniformly treated with surgery, and the same protocol of ...

Prognostic risk factors in medulloblastoma include age, evidence of metastasis at diagnosis, and residual tumor after resection; however, these clinical parameters cannot sufficiently define ...

Medulloblastoma is the most common brain malignancy in children and tremendous advances have recently been made in understanding the pathogenesis of this tumor. The Hedgehog and Wingless signaling ...

My group demonstrated that Medulloblastoma is comprised of at least four distinct diseases (Journal Clinical Oncology, 2011; Cancer Cell, 2017; Nature, 2017) and that there is clinically significant ...