Daily oral treatment with T-614, a member of the methanesulfonanilide family of cyclo-oxygenase 2 inhibitors, might be an alternative to weekly methotrexate therapy for rheumatoid arthritis (RA).

In patients with methotrexate osteopathy (MTXO) insufficiency fractures, continuing MTX led to a significantly higher risk for subsequent fractures, with nearly all patients who continued MTX ...

Methotrexate (MTX) has been used for rheumatoid arthritis (RA) treatment since 1980. It is the most common effective disease-modifying antirheumatic drug (DMARD) for RA, and is considered to be ...