Adverse drug reactions are more common in the liver than in the kidneys for patients with rheumatoid arthritis using ...

Methotrexate (MTX) has been used for rheumatoid arthritis (RA) treatment since 1980. It is the most common effective disease-modifying antirheumatic drug (DMARD) for RA, and is considered to be ...

Previous use of DMARDs, including methotrexate, was permitted, but only if therapy had been discontinued 4 weeks before the study began. However, patients were excluded if they had discontinued ...