The aromatic rings in guanine's structure make it a relatively stable molecule, but it can still undergo various chemical reactions, such as oxidation, reduction, and methylation. One of the most ...

Surprisingly, the methyl groups of the symmetrically methylated CpG sequence are each recognized in a distinct manner. Base specificity results from multiple interactions. The guanine residues ...

and the amount of guanine is equal to the amount of cytosine in a double-stranded DNA molecule. This 1:1 ratio of A:T and G:C is crucial for maintaining the structure and stability of DNA.

a Foundation Model for DNA Methylation. Image Credit: Shutterstock AI In a recent pre-print* study posted to the bioRxiv server, a team of researchers introduced the Cytosine-phosphate-Guanine ...

The study employed high-throughput methods such as barcoded bisulfite amplicon sequencing to measure methylation at androgen-sensitive cytosine-phosphate-guanine (CpG) sites, specifically ...