Figure 2: Characterization of NFT from P301L (JNPL3) mice. Non-transgenic littermates, JN4 or JN25 (WT4R) mice up to 10 months of age lacked these pathological changes; however, we found MC-1 ...

Therefore, with improved efficiency, ES-cell cloning may shorten the time required to generate mutant mice. Figure 1: Targeted insertion at the ROSA26 locus in cloned mice. Our results show that ...

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