As Ran can cause the formation of more microtubules and the reorganization of microtubules that already exist, it is not surprising that both microtubule dynamics and motors are affected by Ran.

The motor domain contains the catalytic site for ATP hydrolysis and the actin or microtubule-binding site. The neck region acts as a lever arm, amplifying the small conformational changes generated by ...

The microtubule-associated protein XMAP215 promotes microtubule growth, but how this occurs has been unclear. To address this question, Gary Brouhard et al. developed a single-molecule ...

The role of centrosomal tubulin glutamylation has remained elusive for decades. Here, a new tool enables precise spatiotemporal control of this modification, showing that it physically recruits ...

Supercomputer simulations by University of Chicago and University of Utah scientists have revealed new behavior happening at microtubule tips, the location where they grow or shrink. This basic ...