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19 天
《Nature》核孔复合体的双向运输路径之谜被揭开
本研究聚焦于核孔复合体(NPC)的核质交换机制,利用MINFLUX技术首次同时监测核输入和输出过程,揭示了核孔中央区域存在重叠的双向运输路径,且运输过程高度受限,具有显著的结构约束和短暂的停顿现象,为理解核质交换的分子机制提供了重要见解 细胞内 ...
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