Replication-dependent histone mRNAs, which encode the most abundant histone proteins, are the only known ... releases the nascent pre-mRNA from the DNA template is the only processing event ...

The latter are small strands of RNA or DNA that can be designed ... broader than ever before. Small molecules can be used to target catalytic proteins, from histone deacetylases to spliceosome ...

Pesavento is an expert in using mass spectrometry to identify biological molecules with ... very important group of proteins ...

Much like the cellular genome, viral genomes must be compacted in virus particles with small basic molecules to maximize space and be poised for gene expression. Some DNA viruses use cellular histone ...

These fatty acids act as molecular switches, binding to histone proteins that package DNA, and regulating gene ... "By pinpointing the gene targets of these molecules, we can unravel how fibre ...