The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...

The latter are small strands of RNA or DNA that can be designed ... broader than ever before. Small molecules can be used to target catalytic proteins, from histone deacetylases to spliceosome ...

There is also the naive idea that each gene of DNA codes for some phenotype, a protein that has some function ... Further, the chromosome structure is affected by a foam-like cloud of histone ...

Much like the cellular genome, viral genomes must be compacted in virus particles with small basic molecules to maximize space and be poised for gene expression. Some DNA viruses use cellular histone ...

“By identifying the gene targets of these important molecules we can understand ... the compounds attached to histone proteins. They then employed advanced DNA sequencing methods to map these ...

To discover the reverse gear of SMC motors, the researchers used an advanced home-built microscope to look at single proteins on individual DNA molecules. That in itself is an impressive ...

Epigenetic modifications, such as DNA methylation and histone modifications, can affect gene expression by ... Long non-coding RNAs are RNA molecules longer than 200 nucleotides that do not encode ...