“The solution we are exploring is to transplant liver progenitor cells.” So far, Ochiya and his team have shown that mouse and rat hepatocytes extracted from livers, even damaged ...

In a lab at Queen Mary University of London, a mouse was born whose existence defied conventional biology. It carried within ...

The study, published in Science Advances, is the first to observe that the buildup of ammonia (hyperammonemia) can harm liver ...

"It is a long way from insights in mouse experiments to bringing a drug ... the function of a gene called Plvap in certain liver cells in mice. The team knew from previous studies that humans ...

These images show slices of mouse liver under the microscope, with tumors outlined in yellow and green indicating the ...

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice.

New research identifies the liver protein PTPRD as a key regulator of metabolic liver disease. Reduced levels of PTPRD disrupt glucose and lipid metabolism, promote liver fat accumulation, and impair ...

The liver is a vital organ, crucial to digestion, metabolism and the elimination of toxins. It has a unique ability, ...

Ammonia buildup damages liver cells by harming mitochondria, leading to cell death and liver injury. An existing drug, YAQ-005, can prevent this damage by halting mitochondrial harm, allowing ...