The complexity of human metastatic cancer is difficult to mimic in mouse models. As a consequence, seemingly successful studies in murine models do not translate into success in late phases of ...
Scientists at the University of Wisconsin Madison and Dana-Farber Cancer Institute recently presented preclinical data for the radiopharmaceutical therapy candidate [177Lu]PNT-6555.
significantly inhibits tumor growth in murine tumor models and is well-tolerated. mPH-762-mediated silencing of PH-762 within the TME may generate memory-specific T cells, promoting IFN-γ release ...
Researchers have described the development of a novel murine model of glioblastoma established with a patient-derived xenograft (PDX) in humanized mice that harbored an almost complete human immune ...