Previous attempts to selectively modulate muscarinic receptors by targeting ... might represent a novel class of antipsychotic drugs.

The drug – a selective muscarinic M4 receptor positive allosteric modulator (PAM) – is designed to have limited effect on dopamine neurotransmission, a mechanism thought to contribute to ...

However, considerably higher concentrations of muscarine are found in fiber cap mushrooms and fool's funnel mushrooms. A team led by Dirk Hoffmeister, Professor at the Institute of Pharmacy at the ...