Muscarinic acetylcholine receptors (mAChRs) are a type of receptor in the brain that respond to the neurotransmitter acetylcholine. They play a crucial role in various brain functions, including ...

The pharmacotherapy of schizophrenia is currently dominated by atypical antipsychotics that primarily target dopaminergic signalling, the dysregulation of which has long been considered to have a ...

A pathway once considered fundamental in Alzheimer’s disease is being studied intensely again, and may soon result in safer, ...

Telephone 0081 43 222 7171 ext 5414; fax 0081 43 226 2160; emailmasatoasahina{at}msn.com OBJECTIVES To assess muscarinic acetylcholine receptors (mAChRs) in the brains of patients with progressive ...

Cobenfy has created a lot of excitement because it applies a new mechanism to treat schizophrenia – it targets muscarinic acetylcholine receptors, found in cell membranes. In particular ...

As per the Brain and Behavior Research Foundation, it combines two compounds called xanomeline and trospium chloride. This is ...

Our recent work (McQuail & Burk, 2006) suggests that cholinergic muscarinic receptors, particularly the muscarinic M1 receptor, are important for mediating the effects of the cortical acetylcholine on ...

Neuropsychiatry Discovery: The lab has a significant research interest in drug discovery for neuropsychiatric disorders, including projects studying the role of the orphan GPCRs, muscarinic ...