Skeletal muscle maintenance and regeneration requires the adult skeletal muscle stem cells or satellite cells. Satellite cells are maintained until late in life when the numbers of satellite cells ...

In the future, we could try to grow cells in the laboratory for disorders for which there are currently no cures—for example, muscle satellite cells for muscular dystrophy, retinal cells for the ...

Under specific 3D culture conditions, the myoblasts self-assembled into SkMO and differentiated further into other mature muscle cell types. Price also identified cells that lacked the myoblast marker ...

They have published their findings in JCI Insight. Also known as muscle stem cells, satellite cells are responsible for muscle growth, repair and regeneration. "Our research highlights how Fn14 ...

More information: Brigette Romero et al, The circular RNA circNFIX regulates MEF2C expression in muscle satellite cells in spastic cerebral palsy, Journal of Biological Chemistry (2024).

Muscle stem cells: Muscle stem cells, or satellite cells, decrease in number as we age. In elderly-human cells DNA methylation suppresses the expression of some genes, including sprouty 1, an ...

Furthermore, we have identified Prox1 transcription factor as an essential regulator of satellite cell differentiation, and our aim is to further understand its function in skeletal muscle physiology ...