Protein unfolding is a key step in the life cycle of many proteins, including certain proteins that are degraded by ATP-dependent proteases or translocated across membranes. The detailed ...

The research team found that the N-terminal attachment of functional ... in labeling diverse peptides and potentially larger ...

The clathrin protein has a three-legged shape and forms cages of different sizes to coat vesicles. At the end of each "clathrin leg," there is the N-terminal domain (NTD) that interacts with ...

View Full Profile. Learn about our Editorial Policies. When I expressed the different protein constructs in neuron cells in culture, I demonstrated that these C-terminal tails determined the ...