In the second half of 2020, Calliditas positioned itself to deliver breakthrough drugs in other orphan indications by acquiring a nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX ...

A Rac GTPase–regulated multiprotein NADPH oxidase is critical for the formation of reactive oxygen species (ROS) in phagocytic leukocytes and other nonphagocytic cells. NADPH oxidase reduces ...