Negative staining is a powerful preparative method for studying particulate specimens. In principle, the specimen is surrounded by heavy metal atoms that act as an electron barrier. Because the ...

Electron microscopes and modern computer image processing allowed University of Tokyo researchers to uncover the correct structure of a protein essential in the immune system, IgM, and a much ...

This communication deals with the fact that after negative staining the ultrastructure of the amyloid fibril can be resolved to filaments, laterally aggregated in varying numbers, in a manner that ...