The skull and facial bones arise from what are known as neural crest cells, which are produced on the back of the embryo and ...

Human embryonic stem cells display neural crest characteristic expression after only five days of culture under WNT induction. Transcription factors SOX10 and PAX7 are seen in green and red ...

Right panels: Lab-grown cortical interneurons from human pluripotent stem cells are tools to study psychiatric disorders. Specific functional, electric firing properties of those neurons are shown by ...

In vertebrates, the skeleton of different regions of the body arises from different precursor cells. Researchers have now ...

Cytora, a clinical stage company developing unique stem cell treatments based on human Oral Mucosa Stem Cells (hOMSCs), reported today successful results of a Phase 1/2a clinical trial for treating ...

We work in two areas. The first is traditional cell and molecular biology, focussed on the molecular mechanisms underlying mesoderm formation, and neural crest induction, and tissue and organ ...

Other iPSC-based models affecting neural crest lineages include Schwann cell and melanocyte-related disorders, including our effort to model human melanoma in pluripotent stem cells. Modeling herpes ...

Additionally, the team used animal models, including mice and chicken embryos, to observe in vivo how ZIC2 regulates the ...