Here we show that the deficit in neurogenesis reflects alterations in the microenvironment that regulates progenitor-cell fate, as well as a defect in the proliferative capacity of the neural ...
In a recent study published in PNAS, researchers from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences explored the regenerative mechanisms behind SCI repair.
The initial four are dopamine-producing neural cells, cardiac progenitor cells, retinal cells, and immune cells. All are derived from human induced pluripotent stem cells (iPSCs) — skin or blood ...
For example, microglia and T cells increased with age, while neural stem cells (NSCs) and oligodendrocyte progenitor cells (OPCs) decreased. T cells showed a substantial increase in numbers across ...
More information: Aaron Stahl et al, Patient iPSC-derived neural progenitor cells display aberrant cell cycle control, p53, and DNA damage response protein expression in schizophrenia, BMC ...