Neurodegenerative conditions such as Parkinson's disease and Alzheimer's involve progressive neuronal loss due to ...

By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.

The first pathological descriptions of the disease 150 years ago already showed that demyelinated axons could degenerate. Recent evidence suggests that multiple sclerosis also affects neurons ...

Medically reviewed by Huma Sheikh, MD Neurons are cells in the body that are responsible for transmitting electrical signals ...

During brain development neurons send out axons, long thin processes. Axons grow towards a target area, where they eventually form synaptic connections with target cells to form functional neuronal ...

1 Neurons are composed of a cell body containing the nucleus, dendrites that receive chemical, electrical, or other signals via receptors or through gap junctions (direct connections between two ...

"Where we have convex and concave patterns because of folding, we have tensile stresses and compressive stresses. When axons move or expand from the core of the brain toward the cortex or outer layer ...

Although firing speed remained unchanged in cylindrical axons, pearled axons showed faster action potentials when sodium channels were periodically spaced at 190nm. Next, the researchers tested the ...

In a recent report in Neuron (22, 89–101, 1999), Marie Filbin and her colleagues at the Hunter College of the City University of New York have elegantly shown how mature neurons can overcome ...

The growth cones aid in the extension of the neuron’s axon. They also detect chemicals in the surrounding environment that help guide the neurons’ projections to the appropriate targets. In mice, ...

Dr. Rasband's team is discovering the functional organization of axons in health as well as disease or injury. The generation, propagation, and modulation of electrical signals in the nervous system ...