Pain processing involves neurons, microglia and astrocytes. The functions of glia extend beyond basic support for neurons. Once activated, they release various classic immune factors that are also ...

Traditionally considered passive 'bystander' cells, which merely offered physical support to neurons, glia—the word is actually derived from the Greek for glue—are, in fact, central actors in ...

Are current neuroinflammation models constraining your research? Traditional animal-derived cell assays lack the complexity of human microglia, limiting their predictive value and impeding progress in ...

Scientists also classify neurons into four groups based on structural differences: Supportive cells, called glial cells, help to regulate neuronal activity. The glia are responsible for cleaning ...

A new model of brain metabolism – the most complex ever generated –shows how altering key chemicals could restore aged cells ...

These three genes encode membrane proteins that transport different metabolites between brain cells, providing them with energy. In the brain, one way that neurons communicate with one another is ...

Technology development of multi-omics: We have developed the first single-cell RNA sequencing platform in Drosophila neurons and glia for studying neural development (Li et al., 2017 Cell; Li et al ...

This manuscript demonstrates that Oct4 overexpression synergizes with Notch inhibition (Rbpj knockout) to promote the conversion of adult murine Müller glia (MG) into bipolar cells. These findings are ...

Vision is one of the most crucial human senses, yet more than 300 million people worldwide are at risk of vision loss due to ...

The increasing implication of glial cells in neurodegenerative diseases makes them an appealing addition to iPSC-based model systems for investigating disease mechanisms. Over the last decade, Dr.

Vision is one of the most crucial human senses, yet over 300 million people worldwide are at risk of vision loss due to various retinal diseases.