hLife由高福院士、董晨院士和Jules A.

在这样的背景下，美国加利福尼亚大学圣地亚哥分校的研究人员开展了一项关于 DUBR（Dppa2 上游结合 RNA，也称为 linc00883）非编码 RNA 的研究。他们发现 DUBR 在人类结肠癌的发生发展中扮演着重要角色，这一发现为癌症研究开辟了新的道路。该研究成果发表在《Functional & Integrative Genomics》杂志上。

Generally, those RNA molecules that do not take the form of mRNA are referred to as noncoding, because they do not encode proteins. The involvement of noncoding mRNAs in many regulatory processes ...

But a team of researchers led by Kishore Guda, associate professor at the Digestive Health Research Institute at the Case Western Reserve School of Medicine, found a special class of ribonucleic acid ...

High expression of the RNA predicted a poor prognosis, the team found. But, Diederichs notes, “we didn’t find a remarkable open reading frame, and we didn’t find any protein expressed from it. We ...

Some researchers hope that new data on cross-generational effects of environmental exposures will help settle the debate. A long noncoding RNA from humans appeared to help the enzyme phenylalanine ...

Small nucleolar RNAs (snoRNAs) are non-coding RNA molecules whose role in gene regulation and association with certain ...

Small nucleolar RNAs (snoRNAs) are non-coding RNA molecules whose role in gene regulation and their association with certain diseases, such as ...

Other ribozymes include self-splicing introns and the RNA component of the enzyme telomerase. Non-coding RNA molecules, such as miRNAs (miRNAs) and long non-coding RNAs (lncRNAs), play essential roles ...

Once thought to be noncoding RNA, circRNA has now been shown to encode functional proteins, challenging conventional RNA biology and opening up novel therapeutic possibilities. Unlike traditional ...